Hearty Roasted Vegetable Butternut Squash Lasagna Recipe

Layers of comfort burst with flavor in this mouthwatering roasted vegetable butternut squash lasagna that redefines classic Italian comfort food.

Autumn’s golden produce shines through each delectable bite of this hearty dish.

Tender butternut squash roasted to caramelized perfection mingles with robust seasonal vegetables, creating a symphony of textures and tastes.

Rich, creamy layers stack between delicate pasta sheets, promising a meal that warms from the first forkful.

Herbs and spices dance through the lasagna, adding depth and complexity to every slice.

Seasonal ingredients come together in a celebration of rustic, wholesome cooking that promises to impress even the most discerning palate.

Gather your ingredients and let this spectacular lasagna become the star of your next meal.

Quick Recipe Overview

Prep Time: 30 minutes

Cook Time: 1 hour 30 minutes

Total Time: 2 hours

Calories: 290 kcal

Servings: 9

What’s in Roasted Vegetable Butternut Squash Lasagna

• Butternut Squash: Sweet autumn star that provides creamy, rich base with silky texture and deep golden color.
• Red Bell Peppers: Vibrant flavor enhancers bringing subtle sweetness and beautiful color to the dish.
• Zucchini: Tender green vegetable adding moisture and delicate earthy undertones.
• Red Onions: Aromatic ingredient delivering sharp, caramelized depth when roasted.
• Garlic Powder: Concentrated seasoning that amplifies overall vegetable complexity.

• Ricotta Cheese: Soft, mild cheese creating smooth and luxurious layering texture.
• Mozzarella Cheese: Melty, stretchy cheese providing golden-brown surface and rich creaminess.
• Parmesan Cheese: Aged cheese delivering sharp, nutty undertones and crispy topping.
• Egg: Binding agent helping ricotta mixture hold structure and enhance richness.

• Milk: Liquid component softening butternut squash puree and creating silky consistency.
• Sugar: Subtle sweetener balancing squash's natural earthiness.
• Cinnamon: Warm spice adding gentle, comforting undertone.
• Nutmeg: Aromatic spice bringing depth and warmth.
• Ginger: Zesty ingredient providing slight kick and complexity.
• Allspice: Rounded spice contributing multi-dimensional flavor profile.
• Salt: Essential mineral enhancing overall taste.
• Black Pepper: Sharp seasoning creating balanced taste sensation.
• Olive Oil: Smooth fat helping vegetables roast evenly and develop rich caramelization.
• Parsley: Fresh herb adding bright, final garnish with vibrant green color.

Cooking Tools for Roasted Vegetable Butternut Squash Lasagna

• Baking Sheets: Large, parchment-lined for roasting vegetables and butternut squash.
• Blender or Food Processor: Essential for creating smooth butternut squash sauce.
• 9×13-inch Baking Dish: Perfect for layering lasagna ingredients.
• Large Pot: For boiling lasagna noodles.
• Small Bowl: Mixing ricotta and egg mixture.
• Cutting Board: Chopping vegetables and preparing ingredients.
• Sharp Knife: Slicing butternut squash and chopping vegetables.
• Measuring Cups and Spoons: Accurately measuring ingredients.
• Foil: Covering lasagna during baking.
• Spatula: Spreading and layering ingredients.

Assembling Roasted Vegetable Butternut Squash Lasagna

• Vegetable Preparation

Chop seasonal vegetables and spread them on a baking sheet. Drizzle with olive oil and sprinkle with seasonings for a flavor-packed base.

• Squash Transformation

Slice butternut squash in half, removing seeds. Roast until tender and caramelized, creating a rich, creamy foundation for the lasagna.

• Smooth Squash Sauce

Scoop out roasted squash flesh and blend with warm spices, creating a silky, aromatic sauce that will elevate the entire dish.

• Noodle Foundation

Cook lasagna noodles until just tender, laying them carefully to create a perfect layered structure for the casserole.

• Creamy Ricotta Layer

Mix ricotta with a hint of egg, creating a luxurious and smooth filling that adds depth and creaminess to the lasagna.

• Layering Magic

Build your lasagna by alternating noodles, roasted vegetables, squash sauce, and cheese. Each layer adds complexity and excitement to the dish.

• Baking Perfection

Cover and bake until the lasagna is bubbling and golden. Allow it to rest briefly, letting the flavors meld and settle.

• Final Flourish

Sprinkle with fresh parmesan and chopped herbs, transforming the dish into a stunning culinary masterpiece ready to impress.

Tips for Roasting and Layering Butternut Squash Lasagna

• Swap seasonal vegetables like bell peppers, zucchini, or eggplant to match market availability and personal preferences.
• Prepare roasted vegetables and butternut squash sauce up to two days in advance, storing separately in airtight containers to streamline assembly and save cooking time.
• Experiment with different cheese combinations like goat cheese, fontina, or gruyère to add unique flavor profiles and creamy textures to the lasagna.
• Incorporate cooked ground turkey, crumbled Italian sausage, or plant-based protein crumbles between layers for additional nutrition and hearty substance.
• Replace traditional lasagna noodles with gluten-free alternatives or thinly sliced zucchini strips to accommodate dietary restrictions without compromising taste and texture.

Serving Up Roasted Vegetable Butternut Squash Lasagna

• Cozy Family Dinner Night: Invite loved ones around the table and enjoy this hearty lasagna as a warm, comforting meal that sparks conversation and connection.
• Wine and Dine Pairing: Complement the rich, earthy flavors with a medium-bodied white wine like Chardonnay or a light red such as Pinot Noir to enhance the overall dining experience.
• Seasonal Side Salad Companion: Serve alongside a crisp mixed green salad with roasted nuts and a light vinaigrette to balance the lasagna's creamy and dense texture, adding freshness to the plate.
• Elegant Vegetarian Centerpiece: Present this lasagna as a stunning main course for vegetarian gatherings, showcasing how plant-based dishes can be sophisticated and deeply satisfying for everyone at the table.

Store and Reheat Roasted Vegetable Butternut Squash Lasagna

• Refrigerator Storage Strategy: Keep leftovers in an airtight container for up to 4 days, ensuring maximum flavor and texture retention. Seal tightly to prevent moisture loss and maintain the lasagna's delicious layers.
• Freezer Friendly Approach: Wrap individual portions or the entire lasagna in double-layered plastic wrap and aluminum foil. Freeze for up to 3 months, creating a convenient make-ahead meal option for busy weeks.
• Reheating Magic: Thaw overnight in the refrigerator, then warm in the oven at 350°F for 20-25 minutes. Cover with foil to prevent excessive drying and maintain the lasagna's creamy consistency.
• Portion Control Wisdom: Slice and separate servings with parchment paper before freezing. This technique allows you to easily grab single portions without defrosting the entire dish, perfect for quick lunches or spontaneous dinner plans.

Rustic Roasted Vegetable Butternut Squash Lasagna

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4.6 from 25 reviews

• Total Time: 2 hours
• Yield: 9 1x

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Description

Hearty roasted vegetable butternut squash lasagna delivers Italian comfort with Mediterranean vegetable layers and creamy ricotta. Seasonal ingredients and bold herbs create a satisfying meal that will delight you at first bite.

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Ingredients

Scale 1x2x3x

• 1 large butternut squash (at least 3 pounds or 1.4 kg)
• 2 medium zucchini, sliced and quartered
• 8 oz (226 g) baby bella mushrooms, sliced
• 1 red bell pepper, julienned or cut into chunks
• 1 yellow or orange bell pepper, julienned or cut into chunks
• 1 red onion, thinly sliced
• 10 lasagna noodles
• 3 cups (12 oz or 340 g) shredded mozzarella cheese
• 1 (15 oz or 425 g) container ricotta cheese
• ½ cup (57 g) grated parmesan cheese
• 2 tbsps olive oil
• ⅔ cup (158 ml) milk (unsweetened almond milk or any milk)
• 1 egg
• 1 tbsp brown sugar or coconut sugar (or pure maple syrup)
• ½ tsp garlic powder
• ½ tsp salt
• ¼ tsp cinnamon
• ¼ tsp nutmeg
• ¼ tsp ginger
• ¼ tsp allspice
• Freshly ground salt and pepper
• Fresh chopped parsley (for garnish)

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Instructions

1. Roasting Vegetables: Preheat oven to 400°F (200°C). Distribute chopped vegetables on a parchment-lined baking sheet, drizzle with olive oil, and season with garlic powder, salt, and pepper.
2. Preparing Butternut Squash: Slice squash lengthwise, remove seeds, and place flesh-side down on a second parchment-lined baking sheet.
3. Vegetable Transformation: Roast vegetables for 30 minutes until golden and caramelized. Continue roasting squash for approximately 1 hour until completely tender.
4. Squash Puree Creation: Scoop out cooled squash flesh and blend with milk, sugar, cinnamon, nutmeg, ginger, and allspice, seasoning with salt and pepper to create a silky, aromatic mixture.
5. Pasta Preparation: Cook lasagna noodles in boiling water for 5-6 minutes, drain, and arrange on a lightly oiled surface to prevent sticking.
6. Ricotta Mixture: Combine ricotta with egg and seasonings to create a creamy layering base.
7. Lasagna Assembly: In a 9×13-inch baking dish, spread a foundational layer of butternut squash mixture. Systematically layer noodles, ricotta, roasted vegetables, mozzarella, and parmesan, repeating until ingredients are evenly distributed.
8. Baking Process: Cover with foil and bake for 25 minutes. Uncover and continue baking 15-20 minutes until cheese develops a golden, bubbling crust.
9. Finishing Touches: Allow lasagna to rest 15-20 minutes for layer stabilization and flavor intensification. Garnish with freshly grated parmesan and finely chopped parsley for visual appeal and herbal brightness.

Notes

• Prep Ahead Wisely: Roast vegetables and butternut squash a day before to save time and enhance flavor development.
• Moisture Management: Pat lasagna noodles dry after boiling to prevent watery layers and ensure structural integrity.
• Cheese Selection Tip: Use freshly grated cheeses for optimal melting and richer taste compared to pre-packaged alternatives.
• Resting Magic: Allow lasagna to rest exactly 15-20 minutes after baking to let layers set and flavors meld perfectly.

• Prep Time: 30 minutes
• Cook Time: 1 hour 30 minutes
• Category: Lunch, Dinner
• Method: Baking
• Cuisine: Italian

Nutrition

• Serving Size: 9
• Calories: 290
• Sugar: 6 g
• Sodium: 400 mg
• Fat: 13 g
• Saturated Fat: 6 g
• Unsaturated Fat: 5 g
• Trans Fat: 0 g
• Carbohydrates: 32 g
• Fiber: 3 g
• Protein: 14 g
• Cholesterol: 70 mg